Pediatric Review: International Journal of Pediatric Research <p><em><strong>ISSN: <a href="" target="_blank" rel="noopener">2349-3267 (Online)</a>, <a href="" target="_blank" rel="noopener">2349-5499 (Print)</a></strong></em></p> Siddharth Health Research and Social Welfare Society en-US Pediatric Review: International Journal of Pediatric Research 2349-5499 The Spectrum of Biopsy Proven Renal Diseases among Children- A Single Centre Study. <p>Introduction: The burden of different renal diseases among children in developing countries is limited due to the absence of a specific registry. In several locations, single or multicenter data on kidney biopsies help to fill this gap.</p> <p>Aim: This study aims to evaluate the histopathological pattern in the south Indian paediatric population in a tertiary care centre. Methods: It is prospective hospital-based research done between the years 2019 to 2021 in 41 cases of less than 14 years of age group.</p> <p>Results: Present study population had a mean age of 72.7 months, with a male predominance. The most common indication for renal biopsy was Steroid Resistant Nephrotic Syndrome, and minimal change disease was the most common histopathological diagnosis by Renal biopsy.</p> <p>Conclusion: This study emphasizes the significance of establishing a regional registry for pediatric renal illness.</p> Dr. M Sudheer Kumar K Raghu Charan B Vijaya Lakshmi Aparna Lakshmi Y Copyright (c) 2022 Author (s). Published by Siddharth Health Research and Social Welfare Society 2022-05-23 2022-05-23 9 2 1 5 Successful Source Identification and Control of an Outbreak of Serratia marcescens Bacteremia in NICU of a Tertiary Care Hospital in Eastern India <p>Introduction: S. marcescens can cause potentially fatal sepsis, especially in premature and low birth weight babies. The result of an outbreak in any hospital is grave and requires thorough environmental sampling for source identification.</p> <p>Purpose: The objective of our study was to identify the source of the Serratia marcescens outbreak among the neonates admitted to the Neonatal Intensive Care Unit (NICU) of a tertiary care pediatric hospital. Seven neonates were affected in this outbreak and the index case, unfortunately, died.</p> <p>Materials &amp;Methods: Apart from attempts to isolate organisms from neonates with sepsis, extensive environmental sampling in the form of swabs were collected from all surfaces like walls, floors, cradles, ventilators etc. and instruments like milk collecting devices, intravenous fluid and drug bottles etc. as well as from hands, stethoscopes, mobile phones of doctors and nursing staffs. Swabs were cultured to isolate S. marcescens, and a sensitivity pattern was noted.</p> <p>Results: Among the 78 samples studied, S. marcescens was isolated from a running intravenous fluid bottle and a normal saline bottle used for reconstituting intravenous fluids for the neonates. These isolates showed the same sensitivity patterns as those obtained from the affected neonates. Elimination of sources, appropriate antibiotic therapy and constant surveillance, achieved successful outbreak control.</p> <p>Conclusions: Extensive environmental sampling to find out the point source, and after that, active surveillance is necessary to control such infections. Besides source control and appropriate antibiotic therapy, implementing and reinforcing routine measures such as hand hygiene are compulsory in these outbreaks.</p> Aniruddha Ghosh Kheya Ghosh Uttam Rafiqul Hassan Partha Pratim Halder Sumon Poddar Copyright (c) 2022 Author (s). Published by Siddharth Health Research and Social Welfare Society 2022-05-23 2022-05-23 9 2 6 13