A Comparative Study of Typhidot and Diazo Test In Early Detection and Diagnosis of Typhoid Fever In Children
Gopal H.1, Sandeep B.2*, Pradeep P.3
DOI: https://doi.org/10.17511/ijpr.2021.i05.05
1 Harisha Gopal, Professor, Department of Paediatrics, MNR Medical College, Hyderabad, Telangana, India.
2* Sandeep Bhaskar, Associate Professor, Department of Paediatrics, Vydehi Medical College, Bangalore, Karnataka, India.
3 Pooja Pradeep, Assistant Professor, Department of Paediatrics, Vydehi Medical College, Bangalore, Karnataka, India.
Introduction: Typhoid fever is an endemic disease and is a significant public health problem in developing countries where water supply and sanitation are substandard. It is one of the most common infectious diseases prevalent in India. The present study was undertaken to compare the sensitivity and specificity of the Typhidot test and Diazo test in suspected Typhoid cases. Materials and Methods: This is a one-year cross-sectional study conducted in Vydehi medical college among 100 children. All the children up to 15 years of age having a history of fever more than three days with symptoms and signs suggestive of Typhoid fever was selected for the study. Blood was taken for blood culture and hypidot . The urine sample was collected for the Diazo test. Results: The majority of the patients (50%) were in the age group of 6-10 years, with the majority of them from the middle class 46%). In the study, 26% of the cases were positive by blood culture, and 33% of the patients were positive by Typhidot M test compared to 34% by diazo test. The sensitivity and specificity of the thypidot test was 84% and 86% compared to the diazo test, which showed 73% and 79%. Conclusion: Typhidot assay is a rapid, easy to perform and reliable diagnostic test with high specificity and sensitivity compared to the Diazo test.
Keywords: Typhoid fever, Typhidot, Diazo test, Blood culture
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, Associate Professor, Department of Paediatrics, Vydehi Medical College, Bangalore, Karnataka, India.Harisha Gopal, Sandeep Bhaskar, Pooja Pradeep, A Comparative Study of Typhidot and Diazo Test In Early Detection and Diagnosis of Typhoid Fever In Children. Pediatric Rev Int J Pediatr Res. 2021;6(5):245-250. Available From https://pediatrics.medresearch.in/index.php/ijpr/article/view/694 |