A Comparative Study Of Typhidot And Diazo Test In Early Detection And Diagnosis Of Typhoid Fever In Children.
Abstract
Introduction: Typhoid fever is an endemic disease and is a significant public health problem indeveloping countries where water supply and sanitation are substandard. It is one of the mostcommon infectious diseases prevalent in India. The present study was undertaken to compare thesensitivity and specificity of the Typhidot test and Diazo test in suspected Typhoid cases.
Materialsand Methods: This is a one-year cross-sectional study conducted in Vydehi medical college among100 children. All the children up to 15 years of age having a history of fever more than three dayswith symptoms and signs suggestive of Typhoid fever was selected for the study. Blood was takenfor blood culture and hypidot . The urine sample was collected for the Diazo test.
Results: Themajority of the patients (50%) were in the age group of 6-10 years, with the majority of them fromthe middle class 46%). In the study, 26% of the cases were positive by blood culture, and 33% ofthe patients were positive by Typhidot M test compared to 34% by diazo test. The sensitivity andspecificity of the thypidot test was 84% and 86% compared to the diazo test, which showed 73%and 79%.
Conclusion: Typhidot assay is a rapid, easy to perform and reliable diagnostic test withhigh specificity and sensitivity compared to the Diazo test.
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