Bacteriological spectrum and immediate outcome of neonatal sepsis in tertiary care centre in South India
Abstract
Introduction: Neonatal septicemia is diagnosed when generalized systemic features of sepsis are associated with pure growth of bacteria from one or more sites. It refers to systemic infection of neonates including Septicemia, Pneumonia, Meningitis, Arthritis, Osteomyelitis and UTI.
Objective: To study the bacteriological profile and antibiotic sensitivity of neonatal sepsis and correlating to outcome.
Materials and Methods: This is a prospective hospital based study in NICU of ASRAM medical college, Eluru.
Period of study: January, 2014 to July, 2015 Selection of cases: 74 Neonates below the age of 28 days with clinical suspicion of neonatal septicemia were included in this study.
Results: Early onset septicemia was present in 49 cases (66%), Late onset septicemia was present in 25 cases (34%). E-coli, Klebsiella and CONS were the most common organisms isolated. Present study shows Gram negative organisms show maximum sensitivity to Imipenem (87.5%). Gram negative organisms show least sensitivity to cefotaxime (25%).
Conclusion: Early-onset septicemia is more common than late-onset septicemia. Gram-negative septicemia is more common than Gram-positive septicemia. Gram-negative organisms are common cause of early-onset septicemia. Mortality is higher in early-onset septicemia and Gram-negative septicemia.
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