Profile of typhoid fever in admitted pediatric patients from tertiary care hospital
Abstract
Introduction: Typhoid fever is preventable infectious diseases caused by gram negative bacteria Salmonella typhi and is still a major public health problem in India.
Objective: The main aim of our study was to find out the clinical profile in admitted pediatric patients of typhoid fever.
Design: Retrospective case study .Subjects: 292 hospitalized Widal positive typhoid fever pediatric cases admitted to tertiary care hospital from1st August 2014 to 31st July 2015.
Methods: Records of all the patients who were discharged with the diagnosis of Widal Positive enteric fever were retrieved, compiled and analyzed.
Results: Out of 292 total patients: 18(6.16 %) were below 2 years of age; 54(18.49%) cases were between 2-5 years; 124(42.46%) were between 5 to 10 years of age and 96 (32.87%) were above 10 years of age. Fever was the main presenting complains in all cases. Vomiting (49.31%), diarrhea (36.98%) and cough (33.56) were common associated complains. Almost all (289, 98.97%) patients were treated with Injection ceftriaxone after positive Widal reports to start with. Only in 62(21.23%) patients, oral Azithromycin was added along with ceftriaxone. 58.20% patients required more than 6 days hospital stay.
Conclusion: The incidence of typhoid fever was 5.63 % amongst the total admitted patients. Typhoid fever is having high morbidity but with availability of third generation cephalosporin, mortality has reduced. 24.65% patients were below 5 years of age which shows changing trends in age of presentation which was considered rare below 5 years of age.
Downloads
References
2. Kothari A, Pruthi A, Chugh TD. The burden of enteric fever. J Infect Dev Ctries. 2008 Aug 30;2(4):253-9. [PubMed]
3. Reller M, Salmonella Species. Principles and Practice of Pediatric Infectious Diseases 3rd Edition 2008: 812-816.
4. Ochiai RL, Acosta CJ, Danovaro-Holliday MC, Baiqing D, Bhattacharya SK, Agtini MD, Bhutta ZA, Canh do G, Ali M, Shin S, Wain J, Page AL, Albert MJ, Farrar J, Abu-Elyazeed R, Pang T, Galindo CM, von Seidlein L, Clemens JD; Domi Typhoid Study Group. A study of typhoid fever in five Asian countries: disease burden and implications for controls. Bull World Health Organ. 2008 Apr;86(4):260-8.
5. Ganesh R, Janakiraman L, Vasanthi T, Sathiyasekeran M. Profile of typhoid fever in children from a tertiary care hospital in Chennai-South India. Indian J Pediatr. 2010 Oct;77(10):1089-92. doi: 10.1007/s12098-010-0196-9. Epub 2010 Sep 30. [PubMed]
6. Verma M, Chhatwal J, Saini V, Singh T. Enteric fever below 2 years of age. Indian Pediatr. 1996 Mar;33(3):229-30. [PubMed]
7. Saha SK, Baqui AH, Hanif M, Darmstadt GL, Ruhulamin M, Nagatake T, Santosham M, Black RE. Typhoid fever in Bangladesh: implications for vaccination policy. Pediatr Infect Dis J. 2001 May;20(5):521-4. [PubMed]
8. Kundu R, Ganguly N, Ghosh TK, Yewale VN, Shah RC, Shah NK; IAP Task Force. IAP Task Force Report: diagnosis of enteric fever in children. Indian Pediatr. 2006 Oct;43(10):875-83.
9. Brooks WA, Hossain A, Goswami D, Nahar K, Alam K, Ahmed N, Naheed A, Nair GB, Luby S, Breiman RF. Bacteremic typhoid fever in children in an urban slum, Bangladesh. Emerg Infect Dis. 2005 Feb;11(2):326-9. [PubMed]
10. Sinha A, Sazawal S, Kumar R, Sood S, Reddaiah VP, Singh B, Rao M, Naficy A, Clemens JD, Bhan MK. Typhoid fever in children aged less than 5 years. Lancet. 1999 Aug 28;354(9180):734-7. [PubMed]
11. Jog S, Soman R, Singhal T, Rodrigues C, Mehta A, Dastur FD. Enteric fever in Mumbai--clinical profile, sensitivity patterns and response to antimicrobials. J Assoc Physicians India. 2008 Apr;56:237-40.
12. Shai Ashkenazi and Thomas G Cleary; Nelson Textbook of Pediatrics 15th edition: 789.
Copyright (c) 2015 Author (s). Published by Siddharth Health Research and Social Welfare Society
This work is licensed under a Creative Commons Attribution 4.0 International License.