A study to compare the pulmonary function test in non-asthmatic allergic and non-asthmatic non-allergic (Apparently Healthy) children-in age group 6-12 years
Abstract
Aims & Objective: To compare Pulmonary Function Test in Non-Asthmatic Allergic and Non-Asthmatic Non-Allergic children.
Background: Many studies have shown that Allergic children are prone to develop Asthma or may have subclinical symptoms of asthma. By comparing pulmonary function test in Allergic children and Non-Allergic children we tried to find out impact of allergy on pulmonary function. We compared the pulmonary functions in the healthy Allergicand Non-Asthmatic children.
Method: This is cross sectional observational case-control study. All 75 children who were selected randomly, in pediatric Out Patient Department (OPD) undergoneBurlingtonent Clinical Questionnaire scoring system, for the clinical assessment of possibility/probability of Allergy (score more than 8). Then, all were evaluated through pulmonary function test by Spirometry. Data of Premedication and Post medication Pulmonary Function parameters were collected and have been compared in relation to Allergic and Non-Allergic possibility. Result were expressed as Mean± SD (standard deviation) and p value was calculated with student paired ‘t’ test and unpaired ‘t’ test.
Results: In our study, statistically significant difference (p<0.01) was found in Pre-bronchodilator Pulmonary Function parameters (%FVC & %FEF25-75) among possible Allergic & possible Non-Allergic group of children, which, however, was non-significant in post bronchodilator Pulmonary function test. On comparing the pre and post medication pulmonary function test parameters (% FEV1, % FVC, % FEV1/FVC, % FEF 25-75, % PEFR(SPIROMETRY), there was statistically significant (p<0.01) positive increment in all these individual lung spirometry parameters in possible Allergic group and not in healthy control group. Although the spirometric parameters did not fulfill the criteria of Asthma, but small airway function parameters were abnormal among possible allergic children.
Conclusion: There is some correlation between clinical suspicion of Allergy and changes in lung parameters in Pulmonary Function Test, which may favoroccurrence of future lung disease and the potential of reversibility in allergic groups by appropriate therapeutic guidance.
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References
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