Thirsty Kidneys: Case Report
Abstract
Contrast induced nephropathy is a reversible form of acute kidney injury occurs following administration of radio-contrast agents. It is associated with serious adverse short and long-term outcomes. The risk is negligible in children with normal renal function but increased in children with underlying kidney disease, dehydration and on nephrotoxic drugs. Contrast induced nephropathy is defined as increase in serum creatinine by >0.5 mg/dL or 25% increase from baseline within 48 to 72 hours of contrast administration. It is one of the commonest cause of hospital acquired acute kidney injury. We present a case of 10 years old boy with normal kidney function who developed acute kidney injury following intravenous contrast administration.
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References
2. Morgan CJ, Zappitelli M, Robertson CM, Alton GY, Sauve RS, Joffe AR, et al. Risk factors and outcomes of acute kidney injury in neonates undergoing complex cardiac surgery. J Pediatr. 2013;162(1): 120–127. doi: 10.1016/j.jpeds.2012.06.054.
3. Slater MB, Anand V, Uleryk EM, Parshuram CS. A systematic reviewofRIFLEcriteriainchildren,anditsapplicationandassociation with measures of mortality and morbidity. Kidney Int.2012; 81:791–798.doi:10.1038/ki.2011.466.
4. John R. Prowle. Acute kidney injury: an intensivist’s perspective. PediatrNephrol. 2014; 29(1):13–21.doi: 10.1007/s00467-013-2411-1.
5. Contrast-induced AKI Kidney International Supplements. KDIGO Clinical Practice Guideline for Acute Kidney Injury.2012; 2:69–88; doi:10.1038/kisup.2011.34.
6. Ajami G, Derakhshan A, Amoozgar H, Mohamadi M, Borzouee M, Basiratnia M, et al. Risk of Nephropathy After Consumption of NonionicContrast Media by Children Undergoing Cardiac Angiography: A Prospective Study. PediatrCardiol 2010;31: 668-673. doi:10.1007/s00246-010-9680-2.
7. Heyman SN, Rosenberger C, Rosen S. Regional alterations in renal haemodynamics and oxygenation: a role in contrast medium-induced nephropathy. Nephrol Dial Transplant 2005; 20 :1-i6-i11. doi:10.1093/ndt/gfh1069.
8. Detrenis S, Meschi M, Musini S, Savazzi G. Lights and shadows on the pathogenesis of contrast-induced nephropathy: state of the art. Nephrol Dial Transplant. 2005; 20:1542- 1550. doi:10.1093/ndt/gfh868.
9. Haase M, Devarajan P, Haase-Fielitz A, Bellomo R, Cruz DN, Wagener G, et al. The outcome of neutrophil gelatinase-associated lipocalin-positive subclinical acute kidney injury: A multicenter pooled analysis of prospective studies. J Am Coll Cardiol.2011;57(17):1752–176.doi: 10.1016/j.jacc.2010.11.051.
10. Mueller C. Prevention of contrast-induced nephropathy with volume supplementation. Kidney Int Suppl. 2006;69: S16-S19. doi.org/10.1038/sj.ki.5000369.
11. Pannu N, Wiebe N, Tonelli M. Prophylaxis strategies for contrast-induced nephropathy. JAMA. 2006 Jun 21. 295;23:2765-2779. doi: 10.1001/jama.295.23.2765. [PubMed]
12. Steven Fishbane. N-Acetylcysteine in the Prevention of Contrast-Induced Nephropathy. Clin J Am Soc Nep hrol. 2008; 3: 281–287. doi:0.2215/CJN.02590607.
Copyright (c) 2018 Author (s). Published by Siddharth Health Research and Social Welfare Society
This work is licensed under a Creative Commons Attribution 4.0 International License.
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