Study of clinical and hematological profile in children with dengue fever in a teaching hospital in Telangana

  • Dr. C. P. V. Ramana Sastry Associate Professor,Department of Paediatrics Malla Reddy Medical College for Women, Telangana, Andra Pradesh, India.
  • Dr. Maram Padmavathi Assistant Professor, Department of Paediatrics Malla Reddy Medical College for Women, Telangana, Andra Pradesh, India.
Keywords: Dengue fever in children, Platelet count, Thrombocytopenia, NS1Ag

Abstract

Introduction: The aim of the study was to determine the clinical and hematological profile in patients with Dengue fever.

Materials and Methods: This was a prospective study done at Malla Reddy Medical College for Women, Telangana, for a period of six months. A total of 110 cases of dengue infection were studied. The patient demographics, clinical symptoms, hematological characteristics such as hemoglobin, total leucocyte count, platelet count, serological studies and abdominal ultrasound findings were noted.

Results: In the present study, 85/110 (77.2%) cases were of dengue fever, 20/110 (18.1%) were dengue hemorrhagic fever (DHF) and 05/110 (4.5%) were of dengue shock syndrome (DSS). Patient age ranged from 0- 12 years. Majority, 55/110 (50%) were among 6-8 years. Males were affected more than females (59% boys and 41% were girls). Moderate thrombocytopenia was seen in 54.5 % of cases and raised hematocrit (>47%) was observed in 22.7 % cases. Most of the cases 75 (68.1%) were noted in September and October.

Conclusion: Dengue is a common viral infection which may have serious consequences especially in children. Simple haematological parameters along with serological tests and ultrasound of abdomen are helpful in the diagnosis and appropriate management of these patients.

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References

1. World Health Organization; Dengue and Dengue Hemorrhagic fever. Available in www.who.int/media centre/factsheets./ fs117/en/.

2. Guzmán MG, Kourí G. Dengue: an update. Lancet Infect Dis. 2002 Jan;2(1):33-42.[pubmed]

3. Tanner L, Schreiber M, Low JG, et al. Decision tree algorithms predict the diagnosis and outcome of dengue fever in the early phase of illness. PLoSNegl Trop Dis. 2008 Mar 12;2(3):e196. doi: 10.1371/journal.pntd.0000196.[pubmed]

4. Manock SR, Jacobsen KH, de Bravo NB, et al. Etiology of acute undifferentiated febrile illness in the Amazon basin of Ecuador. Am J Trop Med Hyg. 2009 Jul;81(1):146-51.[pubmed]

5. Huy R, Buchy P, Conan A, et al. National dengue surveillance in Cambodia 1980-2008: epidemiological and virological trends and the impact of vector control. Bull World Health Organ. 2010 Sep 1;88(9):650-7. doi: 10.2471/BLT.09.073908. Epub 2010 Apr 7.[pubmed]

6. Sam SS, Omar SF, Teoh BT, et al. Review of Dengue hemorrhagic fever fatal cases seen among adults: a retrospective study. PLoSNegl Trop Dis. 2013 May 2;7(5):e2194. doi: 10.1371/journal.pntd.0002194. Print 2013.[pubmed]

7. Sicuro Correa L, Hokerberg YHM, Oliveira RdVCd, Barros DMD. S, Alexandria HAF, Daumas RP, et al. Use of Warning Signs for Dengue by Pediatric Health Care Staff in Brazil. PLoS ONE 2016;11(10): e0163946.[pubmed]

8. Potts J A, et al. 2010 Prediction of dengue disease severity among Thai pediatric patients using early clinical laboratory indicators PLoSNegl. Trop. Dis. 4 1-7.[pubmed]

9. Mishra S, Ramanathan R, Agarwalla SK. Clinical Profile of Dengue Fever in Children: A Study from Southern Odisha, India. Scientifica 2016, Article ID 6391594, 6 pages.

10. Srinivasa S, Nawab T, NairCC. Clinical profile and ultrasonographic findings in children with dengue fever.CurrPediatr Res 2014;18 (2):87-90.

11. Jain H. Clinical profile and outcome of dengue fever in hospitalized children of South Rajasthan, India. Int J ContempPediatr. 2016;3(2):546-549.

12. Kumar BV,Simna L, Kalpana D, Kailas L. Clinical profile and outcome of children admitted with dengue fever in a tertiary care hospital in South India. Indian J Child Health 2018;5(1);32

13. Alam AS, Sadat SA, Swapan Z, Ahmed AU, Karim MdK, Paul HK, et al. Clinical profile of dengue fever in children. Bangladesh J Child Health 2009;33(2):55-58.
Study of clinical and hematological profile in children with dengue fever in a teaching hospital in Telangana
CITATION
DOI: 10.17511/ijpr.2019.i01.05
Published: 2019-01-31
How to Cite
Dr. C. P. V. Ramana Sastry, & Dr. Maram Padmavathi. (2019). Study of clinical and hematological profile in children with dengue fever in a teaching hospital in Telangana. Pediatric Review: International Journal of Pediatric Research, 6(1), 29-34. https://doi.org/10.17511/ijpr.2019.i01.05
Section
Original Article