Cholestatic hepatitis in a child with typhoid fever –a case report

  • Dr. Sheo Pratap Singh Department of Pediatrics, S.N. Medical College, Agra.
  • Prof (Dr). R. Dayal Department of Pediatrics, S.N. Medical College, Agra.
  • Prof (Dr). Neeraj Kumar Department of Pediatrics, S.N. Medical College, Agra.
  • Dr. Madhu Singh Department of Pediatrics, S.N. Medical College, Agra.
  • Dr. L.K. Gupta Associate Professor, Department of Pediatrics, Government Medical College, Firozabad.
DOI: https://doi.org/10.17511/ijpr.2019.i10.01
Keywords: Typhoid fever, Enteric fever, Clinical manifestations

Abstract

Typhoid fever is a common infectious disease in developing countries. It is caused by Salmonella typhi. Salmonella is a genus of the family Enterobacteriaceae. They are rod-shaped, Gram-negative, facultative anaerobic bacteria, most of which are motile by perit¬richous flagella (which bear H antigen [s]). S. Typhi is taxonomically designated as Salmonella enterica subspecies enterica serovar Typhi. In addition to the H antigen (s), 2 polysaccharide surface antigens aid in further characterization of S. enterica, namely the somatic O antigen and capsular Vi (virulence) anti¬gen. Vi antigen is associated with resistance to complement-mediated bacterial lysis and resistance to complement activation by the alternate pathway.

Salmonella enterica serovars Paratyphi A and Paraty¬phi B (and uncommonly Paratyphi C) cause a disease (paratyphoid fever) that is clinically indistinguishable from typhoid fever, particularly in parts of Asia. Typhoid fever and paratyphoid fever are collectively termed enteric fever.

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CITATION
DOI: 10.17511/ijpr.2019.i10.01
Published: 2019-10-31
How to Cite
Dr. Sheo Pratap Singh, Prof (Dr). R. Dayal, Prof (Dr). Neeraj Kumar, Dr. Madhu Singh, & Dr. L.K. Gupta. (2019). Cholestatic hepatitis in a child with typhoid fever –a case report. Pediatric Review: International Journal of Pediatric Research, 6(10), 501-504. https://doi.org/10.17511/ijpr.2019.i10.01
Issue
Vol 6 No 10 (2019): OCTOBER
Section
Case Report

Copyright (c) 2019 Author (s). Published by Siddharth Health Research and Social Welfare Society

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