Spectrum of pediatric malignancy- A cancer hospital-based study
Abstract
Objective: Childhood malignancy being a significant cause of mortality among children. The aim of the study is to find out the epidemiology of tumours in children in our region below <14 years age who presented to tertiary care Cancer hospital, Bhopal, M.P. for period of four years (2015- 2018).
Methodology: All children with cancer, aged 1-14 years diagnosed by mean of histological and cytological examination during a period of 4 years were reviewed.
Results: During the period of four years 275 patients were diagnosed as having paediatric malignancies. According to year wise distribution highest incidence of cases were found in 2016 (32.72%). The highest number of cases, 96(35%) were in 10-14 years of age group and mean age was 7.43 with SD 4.0. Male were affected more than females with ratio of 2.66:1. It was observed that haematological malignancies were more common 172(62.54%) than the non haematological malignancies 103(37.45%). Leukemia 150 (54.54%) is most common pediatric cancer amongst which Acute lymphoblastic leukemia is most common haematological malignancy. Overall, it was found that most common cancer group in the present study were leukemia (54%) followed by lymphoma (8.36%), Brain tumours (7.27%) and Sarcoma (7.27%).
Conclusion: Although the exact incidence rate cannot be provided by this hospital-based study, the information is useful in showing distribution patterns of childhood malignancy in this region.
Downloads
References
Sharma S, Mishra K, Agrawal S, Khanna G. Solid tumors of childhood. Indian J Pediatr.2004;71:501-504. doi: https://doi.org/10.1007/BF02724289.
Lanier AP, Holck P, Ehrsam Day G, Key C. Childhood cancer among Alaska Natives, Pediatr.2003;112(5):e396. doi: https://doi.org/10.1542/peds.112.5.e396.
Kusumakumary P, Jacob R, Jothirmayi R, Nair MK. Profile of pediatric malignancies. A ten years study. Indian Pediatr.2000;37:1234-1238.
Steliarova-Foucher E, Colombet M, Ries LAG, Moreno F, Dolya A, Bray F, et al. International incidence of childhood cancer,2001-10: A population-based registry study. Lancet Oncol. 2017;18(6):719-731. doi: https://doi.org/10.1016/S1470-2045(17)30186-9.
Fethi A, Amani F, Bahadoram M. Epidemiology of childhood cancer in Northwest Iran. Asian Pac J Cancer Prevent.2015;16(13):5459-5462. doi: http://dx.doi.org/10.7314/APJCP.2015.16.13.5459.
Jafroodi M, Ghandi Y. Epidemiologic evaluation of pediatric malignancies in 17 shahrivar hospital. J Guilan Univ Med Sci.2009;17(68):14-21.
Ghasemi M, Karami H, Abedian-Kenari S, Kianifar S. Patterns of cancer in the children admitted in Avicenna Hospital in Sari, Iran. Int J Haematol: Oncol Stem Cell Res.2011;5(2):29-33.
Das S, Paul DK, Anshu K, Bhakta S. Childhood cancer incidence in India between 2012 and 2014: Report of a population – Based cancer Registry. Indian Pediatr.2017;54(12):1033-1036. doi: https://doi.org/10.1007/s13312-017-1207-y.
Arora RS, Eden T, Kapoor G. Epidemiology of childhood cancer in india. Indian J Cancer.2009;46(4):264-273. doi: https://doi.org/10.4103/0019-509X.55546.
Jabeen S, Haque M, Islam M.J, Talukdar M. H. Profile of pediatric malignancies. A five years study. J Dhaka Med Coll.2010;19(1):33-38. doi: https://doi.org/10.3329/jdmc.v19i1.6249.
Hazarika M, Krishnatreya M, Bhayan C, Saikia BJ, Kataki AC, Nandy P, et al. Overview of childhood cancers at a Regional cancer centre in North-East India. APJCP.2014;15(18):7817-7819. doi: https://doi.org/10.7314/APJCP.2014.15.18.7817.
Boroumand H, Moshki M, Khajavi A, Darabian M, Hashemizadeh H. Epidemiology of childhood cancer in Northeast of Iran, Iran J Ped Hematol Oncol. 2016;17(1):9-15. Available at http://ijpho.ssu.ac.ir/article-1-281-en.html
Bhalodia JN, Patel MM. Profile of pediatric Malgnancy: A three years study. Nat J Comm Med.2011;2(1):24-27.
Punia RS, Mundi I, Kundu R, Jindal G, Dalal U, Mohan H. Spectrum of nonhematological pediatric tumors. A clinicopathologic study of 385 cases. Indian J Med Paediatr Onco.2014;35(2):170-174. doi: https://dx.doi.org/10.4103%2F0971-5851.138995.
Hashemizadeh H, Boroumand H, Noori R, Darabian M. Socioeconomic status and other characteristics in childhood leukemia. Iran J Pediatr Hematol Oncol. 2013;3(1):182-186.
Holmes L, Vanderberg j, McClarin L, Dabney K. Epidemiologic, racial and healthographic mapping of Delaware pediatric cancer. Int J Environ Res Public Health. 2015;13(1):49. doi: https://doi.org/10.3390/ijerph13010049.
Amini H, Seifi M, Niazi-Esfyani S, Yunesian M. Spatial epidemiology and pattern analysis of childhood cancers in Tehran Iran. J Advan Environ Health Res.2014;2(1):30-37. doi: https://dx.doi.org/10.22102/jaehr.2014.40141.
Copyright (c) 2020 Author (s). Published by Siddharth Health Research and Social Welfare Society
This work is licensed under a Creative Commons Attribution 4.0 International License.
OAI - Open Archives Initiative
