Transfusion practices in the pediatric and neonatology departments of Soavinandriana hospital center

  • Rosa Lalao Tsifiregna Department of Pediatrics and Neonatology, Hospital Center of Soavinandriana, Antananarivo, Madagascar
  • Mbola Rakotomahefa Narison Pediatric Oncology Pilot Unit, Joseph Ravoahangy Andrianavalona Hospital Center Antananarivo Madagascar
  • Filaminantsoa Nambininjanahary Department of Pediatrics and Neonatology, Hospital Center of Soavinandriana, Antananarivo, Madagascar
  • Annick Lalaina Robinson Child Mother Hospital, Anatananarivo, Madagascar
  • Olivat Rakoto Alison Hematology Unit, Joseph Ravoahangy Andrianavalona Hospital Center, Antananarivo, Madagascar
Keywords: Blood transfusion, Practices, Antananarivo

Abstract

Blood transfusion is an important part of day-to-day clinical practice. The main objective of this work is to describe transfusion practices in the Pediatrics and Neonatology Department of the Hospital Center of Soavinandriana.

Methods: A prospective observational study of 6 months has been conducted. All requests to Department of Pediatrics and Neonatology for blood for transfusion for children aged less than 14 years were identified prospectively. The variables studied were: patients’ characteristics (age, gender) reason for hospitalization, paraclinical examinations (blood count and formula before transfusion, ABO and Rhesus grouping), the presented pathology, the indicated transfusion: nature, incidents during and after transfusion and the outcome of the pathology (healing, death).

Results: The incidence was 6.54%, 33 patients had a blood transfusion. The sex ratio was 1.35. The average age is 46.06 months. Skin pallor was the main reason for hospitalization, which represented 18.18% of the cases. The average hemoglobin level was 8.08 g/dl. The O and rhesus positive blood group was the predominant in this work. The blood products which were used were: red blood cell (n=20, 54.05%), whole blood (n=15, 40.54%), fresh frozen plasma (n=1, 2.70%), platelets concentrate (n=1, 2.70%). The National Center for Blood Transfusion of the Joseph Ravoahangy Andrianavalona University Hospital Center had delivered the vast majority of the used blood bags.

Conclusion: The packed red blood cell was used the most and the hospital blood bank did not have enough labile blood products. It is therefore essential to improve the structures for the preparation of blood and its derivatives, in order to make all varieties of labile blood products accessible.

Downloads

Download data is not yet available.

References

MayukuFukiau G, MbayoKalumbu F, SituakibanzaNaniTumaH. Evaluation of the effectiveness of blood transfusion in children in Kinshasa: experience of three medical trainings. Transfusion Clinique etBiologique. 2013;20:361. DOI : https://doi.org/10.1016/j.tracli.2013.03.248

Navarro C, Ducher E, Tas H, Chabre C, F. Deméocq, P. Fabrigli et al. Transfusion practices in pediatrics: retrospective monocentric study, Arch Ped. 2011 November; 18:1154-61. DOI : 10.1016/j.arcped.2011.08.010

Nguefack1 F, Chelo1 D, Tejiokem MC, Pondy A, Njiki kinkela1 MJ, Dongmo R and al. Frequency of severe anemia in children aged 2 months to 15 years at Mother and Child Centre of the Chantal Biya Foundation Yaounde, Cameroon. Pan Afr Med J. 2012; 12: 46.Available online at: http://www.panafrican-med-journal.com/content/article/12/46/full/

Rakotoaritiana RU. Prescription of blood transfusion at the Fianarantsoa University Hospital [Thesis]. Human medicine: Antananarivo; 2013; n ° 8501. 45p. Available online at: http://biblio.univ-antananarivo.mg/pdfs/rakotoaritianaRuphineU_MED_DOC_13.pdf

Rakotovao AF. Epidemio-clinical study of sickle cell anemia in the pediatric service HJRB [Thesis]. Human medicine: Antananarivo; 2012; n ° 8352. 60p. Available online at: http://biblio.univ-antananarivo.mg/pdfs/rakotovaoAndriantsihoaranaF_MED_DOC_12.pdf

Nabwera HM, Greg F, Jay S, Douglas D, Kishor M. Pediatric blood transfusion practices at a regional referral hospital in Kenya. Transfusion 2016 Nov;56(11):2732-2738. DOI: 10.1111/trf.13774

Nyashadzaishe M, Star K, Oliver H, Brian E, Isaac K, David A et al. Profiles of blood and blood component transfusion recipients in Zimbabwe. Blood Transf. 2015; 13: 600-9. DOI : 10.2450 / 2015.0019-15.

Julius T, Philip A, Morris O, Susan G, Boniface M, Wycliffe N et al. Blood Transfusion Delay and Outcome in County Hospitals in Kenya. Am Soc Too. Med Hyg. 2017; 96 (2): 511-7. DOI: 10.4269 / ajtmh.16-0735

Chelo D, Monebenimp F, Francisse X, Oouogue T, Abena Obama MT. Determinants of mortality of children under-5 years transfused in two pediatric services of Yaounde. Cameroon Health Sci. 2016 March; 17 (1). Available online at: https://www.hsd-fmsb.org/index.php/hsd/article/view/613/pdf_313

Dan V, Koumakpai S, Hazoume F, Latoundji S, Ayivi B. Transfusion problems in the pediatrics and medical genetics department of the national hospital and university center of Cotonou. Med Afr Noire. 1992; 39 (7). Available online at: https://pdfs.semanticscholar.org/528e/1f2ca2b686df1b26fa8085a8ecbac5a01a8e.pdf?_ga=2.126103373.1723664831.1592676687-1773324822.1592676687

Okoko AR, Galiba FO, Oko A, Moyen-Engoba, Moyen G. Pediatric transfusion activity at Brazzaville University Hospital Centre. Rev CAMES. 2008;6:30-3.

Arnaud F, Simeoni U. Blood Product Transfusion in the Neonatal Period. TransfusClin Biol. 2005 Oct;12(4):336-41. DOI: 10.1016/j.tracli.2005.07.003.

Roger P, Kelodjoue S, Dzossa D, Fomo M, Niekou R, Jazet E et al. Demographic and Health Survey and with Multiple Indicators. National Institute of Statistics (INS), Ministry of Planning, Programming, Development and Spatial Planning, Ministry of Public Health, Yaoundé, Cameroon. Calverton, Maryland, USA: INS and ICF International. 2012 September.

DjeutchouangSayang C. Interest of the use of rapid diagnostic tests for malaria on the cost and effectiveness of the management of febrile patients in Yaoundé, Cameroon [Thesis]. Human medicine: Marseille, France; 2010. 98p. Available online at: https://www.theses.fr/2010AIX20663.pdf

KedyKoum D, NgouadjeuDonghoTsakeu E, Ngo Sack F, Tchienrg P, Ngalagou M et al. Clinical and Biological Aspects of Pediatric Anemia in a Urban District Hospital in Cameroon. Pan Afr Med J. 2013 Nov 11;16:91. DOI: 10.11604/pamj.2013.16.91.3307.

Proulx F, Martinot A, Leclerc F, Lacroixi J, Gauvinl F, Chaibou M et al. Transfusions of globularconcentrate in pediatricresuscitation. Réa Urg.2000; 9(5):339-344 .

DOI: 10.1016/S1164-6756(00)90073-2

Rakotosalama N. Transfusion practices in the emergency and intensive care unit, CHU Mahajanga Androva. [Thesis]. Human medicine: Mahajanga; 2005 December; 55p. Available online at:

http://biblio.univ-antananarivo.mg/pdfs/rakotosalamaNiriantsoaR_MED_DOC_05.pdf

Rahanitrarisoa M. Evaluation of transfusion practice in the surgical resuscitation department, CHU Ampefiloha [Thesis]. Human medicine: Antananarivo; 2004 May; n ° 6959.54p. Available online at: http://biblio.univ-antananarivo.mg/pdfs/rahanitrarisoa_med_doc_04.pdf

Libite P, Tchamda C, Mosoko J, Nouetagne S, Makang J, Barrère B et al. Demographic Survey and Health, Cameroon 2004. 2005 June; 3: 165-75. Available online at: https://www.dhsprogram.com/pubs/pdf/FR163/FR163-CM04.pdf

Garba M. Transfusion requirements in the haematology/medical oncology and internal medicine department of the CHU du Point "G" from January 1998 to December 2003. [Theses]. Faculty of Medicine: Bamako ; 2004.56p.Available online at:http://www.keneya.net/fmpos/theses/2005/med/pdf/05M253.pdf

Ouethy N. Analysis of transfusion activities in the Pediatrics Department of the Gabriel Touré hospital and university center [thesis]. Human medicine: Bamako; 2000; # 29. 61p.

Chobli M. Blood transfusion in Africa: Which blood for which patients in Africa? Cotonou Faculty of Medicine - Benin Republic. RAMUR 2011;16(1): 1-2. Available online at: https://saranf.net/IMG/pdf/corps_journal_definitif.pdf

CITATION
DOI: 10.17511/ijpr.2020.i05.04
Published: 2020-06-30
How to Cite
Lalao Tsifiregna, R., Rakotomahefa Narison, M., Nambininjanahary, F., Lalaina Robinson, A., & Rakoto Alison, O. (2020). Transfusion practices in the pediatric and neonatology departments of Soavinandriana hospital center. Pediatric Review: International Journal of Pediatric Research, 7(5), 210-216. https://doi.org/10.17511/ijpr.2020.i05.04
Section
Original Article