Study of anemia in hospitalised infants with special reference to its risk factors

  • Dr. Ami Himanshu Patel Department of Pediatrics, GCS Medical Collage, Hospital and Research Centre, Ahmedabad, Gujarat, India.
  • Dr. Prarthana Kharod Patel Department of Pediatrics, GCS Medical Collage, Hospital and Research Centre, Ahmedabad, Gujarat, India.
Keywords: Anemia, Infants, Iron deficiency, Risk factors

Abstract

Background: Anemia is a major nutritional problem in India. Anemia in infancy and early childhood affects growth and development and is associated with increased morbidity and mortality. The aim of this study was to determine the prevalence, severity and types of anemia and study the risk factors for anemia in hospitalised infants.

Methods: A prospective study was conducted at a tertiary care hospital in Western India from July 2016 to December 2017. Complete hemogram of all hospitalised infants between 6-12 months of age was done and those with haemoglobin levels<11g/dl were considered anemic.

Results: Out of 206 hospitalised infants,131(63.6%) had anemia. Male: female ratio was1.3:1. The most common illness for which they were admitted was respiratory tract infections.35.1% of the anemic infants had low birth weight, 19.1% were born prematurely and 59.5% had a history of maternal anemia. Only 42% were exclusively breast fed till 6 months of age and improper complementary feeding practices was observed in 61.8% of infants. Mild, moderate and severe anemia was seen in 41.2%, 50.4% and 8.4% infants respectively. The most common type of anemia was microcytic hypochromic anemia (67.2%).

Conclusion: Anemia is a major problem in infants with a high prevalence. Most infants have mild to moderate anemia and the most common type is microcytic hypochromic anemia most likely due to iron deficiency. Preterm gestation, absence of exclusive breastfeeding, consumption of cow’s milk, improper complementary feeding practices and presence of maternal anemia were the risk factors found to be associated with development of anemia in the present study.

Downloads

Download data is not yet available.

References

International Institute for Population Services and ICF. 2017. National Family Health Survey (NFHS-4), 2015-2016: India. Mumbai: IIPS. Available at http://rchiips.org/NFHS/NFHS-4Reports/India.pdf.

Nutritional anemias.Tools for effective prevention and control, Geneva:World Health Organization.2017. Available at http://apps.who.int/iris/bitstream/handle/10665/259425/9782541513067_eng.pdf.

World Health Organization. Indicators for assessing infant and young child feeding practices 2010.Available at http://apps.who.int/iris/bitstream/10665/44368/1/9789241599757_eng.pdf.

Kumar N, Shekhar C, Kumar P, Kundu AS. Kuppuswamy's socioeconomic status scale-updating for 2007. Indian J Pediatr. 2007;74(12):1131-1132.

WHO child growth standards. Length-for-age, weight- for-age, weight-for-length, weight-for-height and body mass index for age. Methods and Development. Department of Nutrition for Health and Development. Geneva: World Health Organization, 2006: 50-221. Available at http://www.who.int/childgrowthstandards/Technical_report.pdf.

Sahana KS, Ghaliyah K, Anitha P, Prakash S. Study of anemia in hospitalized infants at a tertiary care hospital. Ntl J of Community Med. 2015;6(2):22-27.

Saba F, Poornima S, Balaji PA, Varne SR, Jayashree K. Anemia among hospitalized children at a multi-speciality hospital, Bangalore (Karnataka), India. J Family Med Prim Care. 2014(1);3:48-53. doi:10.4103/2249-4863.130275.

Verghese S, Kamalakarababu SK, Vadakkedam S. Prevalence and severity of anemia among hospitalised children aged 6-59 months. J Evolution Med Dent Sci. 2017; 6 (82) :5750-5754. doi:10.14260/jemds/2017/1247.

Rawat R, Saha KK, Kennedy A, Rohner F, Ruel M, Menon P. Anaemia in infancy in rural Bangladesh: contribution of iron deficiency, infections and poor feeding practices. Br J Nutr. 2014;111(1):172-181. doi:10.1017/S0007114513001852.Epub2013Jun17.

Spinelli MG, Marchioni DM, Souza JM, Souza SB, Szarfarc SC. [Risk factors for anemia among 6- to 12-month-old children in Brazil]. Rev Panam Salud Publica. 2005; 17(2):84-91. doi:10.1590/s1020-498920 05000200004.

Silva DG, Priore SE, Franceschini SD. Risk factors for anemia in infants assisted by public health services: the importance of feeding practices and iron supplementation. Jornal de Pediatria. 2007;83(2):149-156. doi:10.2223/JPED.1603.

Ramakrishnan K1, Harish PS. Hemoglobin level as a risk factor for lower respiratory tract infections. Indian J Pediatr. 2006;73(10):881-883.

Siegel EH, Stoltzfus RJ, Khatry SK, Leclerq SC, Katz J, Tielsch JM. Epidemiology of anemia among 4- to 17-month-old children living in south central Nepal. Eur J Clin Nutr. 2006; 60(2):228-235. doi:10.1038/sj.ejcn.1602306.

Soliman AT, Al Dabbagh MM, Habboub AH, Adel A, Humaidy NA, Abushahin A. Linear growth in children with iron deficiency anemia before and after treatment. J Trop Pediatri. 2009;55(5):324-327. doi:10.1093/tropej/fmp011.Epub2009Mar4.

Gupta SK, Bansal D, Malhi P, Das R. Develop-mental profile in children with iron deficiency anemia and its changes after therapeutic iron supplementation. The Indian Journal of Pediatrics. 2010;77(4):375-379. doi:10.1007/s12098-010-0046-9.

Shakur YA, Choudhury N, Hyder SM, Zlotkin SH. Unexpectedly high early prevalence of anaemia in 6-month-old breast-fed infants in rural Bangladesh. Public Health Nutr. 2010;13(1):4-11. doi: 10.1017/S136 8980009005886.Epub2009May28.

Joo EY, Kim KY, Kim DH, Lee JE, Kim SK. Iron deficiency anemia in infants and toddlers. Blood Res. 2016; 51(4): 268-273. doi:10.5045/br.2016.51.4.268. Epub 2016 Dec 23.

Monajemzadeh SM, Zarkesh MR. Iron deficiency anemia in infants aged 12-15 months in Ahwaz, Iran. Indian J Pathol Microbiol. 2009;52(2):182-184.

Meinzen-Derr JK, Guerrero ML, Altaye M, Ortega-Gallegos H, Ruiz-Palacios GM, Morrow AL. Risk of infant anemia is associated with exclusive breast-feeding and maternal anemia in a Mexican cohort. J Nutr. 2006;136(2):452-8. doi:10.1093/jn/136.2.452

Khandelia R. A study of anemia in hospitalised infants at a tertiary care hospital. GJRA. 2007;6(8):145-46

Jain S, Chopra H, Garg SK, Bhatnagar M, Singh JV. Anemia in children: early iron supplementation. Indian J Pediatr. 2000; 67 (1): 19-21. doi: 10.1007/bf 02802628.

Baker RD, Greer FR; Committee on Nutrition American Academy of Pediatrics. Diagnosis and prevention of iron deficiency and iron-deficiency anemia in infants and young children (0-3 years of age). Pediatr. 2010; 126 (5): 1040-1050. doi: 10.1542/peds.2010-2576. Epub 2010 Oct 5.

Kumar A. National nutritional anaemia control programme in India. Indian J Public Health. 1999;43 (1): 3-5.

CITATION
DOI: 10.17511/ijpr.2019.i10.06
Published: 2019-10-31
How to Cite
Dr. Ami Himanshu Patel, & Dr. Prarthana Kharod Patel. (2019). Study of anemia in hospitalised infants with special reference to its risk factors. Pediatric Review: International Journal of Pediatric Research, 6(10), 527-533. https://doi.org/10.17511/ijpr.2019.i10.06
Section
Original Article