Patent ductus arteriosus – clinical profile and outcome after treatment in a tertiary care hospital
Abstract
Background: Patent ductus arteriosus (PDA) is the commonest congenital heart disease seen in neonatal ICU.
Methods: A prospective observational study was conducted in the neonatal intensive care unit of Vydehi institute of medical sciences between January 2013 to December 2016. Neonates suspected to have congenital heart disease in the NICU on the basis of history clinical examination, pulse oximetry, chest X ray were included in the study and confirmed by 2D echocardiography and colour Doppler study. PDA if found hemodynamically significant treated with a three-day course of Ibubrufen and data analyzed.
Results: A total of 2658 cases were admitted in the NICU during the study period of which 1974 cases were screened for CHDs. Out of 1974 babies, Echo done showed 65 babies had PDA. Out of 65 cases with PDA 32 were hemodynamically significant. About 25 out of 32 cases had responded to treatment with Ibubrufen. Ductus were closed in 5 out of 9 large PDAs. About 48% of the PDAs were closed by 5th day of starting the treatment.
Conclusion: The study shows PDA is a commonest Acyanotic CHD in NICU and early administration of the drug is helpful in closure, avoiding surgical correction later and also mortality.
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Copyright (c) 2017 Author (s). Published by Siddharth Health Research and Social Welfare Society
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